MIFIDPRU

MIFIDPRU DISCLOSURES

1. Introduction

The Investment Firm Prudential Regime (‘IFPR’) is the FCA’s prudential regime for MiFID investment firms which aims to streamline and simplify the prudential requirements for UK investment firms. The IFPR came into effect on 1 January 2022 and its provisions apply to Medicxi Ventures (UK) LLP (“the Firm”) as an FCA authorised and regulated firm.

Under the IFPR, the Firm is categorised as a small and non-interconnected (‘SNI’) MIFIDPRU investment firm.

The Firm is required to publish disclosures in accordance with the provisions outlined in MIFIDPRU 8 of the FCA Handbook. This disclosure document covers all aspects of the disclosure requirements within the scope of the MIFIDPRU rules applicable to SNIs that have not issued additional tier 1 instruments. Specifically, disclosure relating to the Firm’s remuneration policy and practices.

The Firm is not a member of a UK Consolidation Group. The disclosure is prepared annually on an individual basis. The Firm will consider making more frequent public disclosure where particular circumstances demand it, for example, in the event of a major change to its business model or where a merger has taken place.

The Firm believes that its qualitative disclosures are appropriate to its size and internal organisation, and to the nature, scope and complexity of its activities.

This disclosure has been ratified and approved by the Members of the Firm.

The annual audited accounts of the Firm set out further information which complements the information in this disclosure. The audited accounts are freely available from UK Companies House.

This document does not constitute any form of financial statement on behalf of the Firm. The information contained herein has been subject to internal review but has not been audited by the Firm’s external auditors.

2. Objectives

This document sets out the public disclosure under MIFIDPRU 8 for the Firm as of 31 December 2025, which is the Firm’s accounting reference date.

As a MIFIDPRU investment firm, we must establish and implement disclosure requirements to provide investors, stakeholders and wider market participants an insight into how the Firm is run. This disclosure sets out the overarching requirements that apply to the Firm.

3. Policy and Disclosure Validation

The Firm is committed to having robust internal controls to ensure the completeness, accuracy, and compliance with the relevant public disclosure regulatory requirements.

This document has been subject to internal governance and verification process, and approval by the Members in line with the Public Disclosure Policy that the Firm has adopted to ensure compliance with the regulatory requirements contained in MIFIDPRU 8.

The Policy requires internal challenge and oversight prior to approval and publication.

4. Remuneration Policies and Practices

Introduction

As a MIFIDPRU investment firm, we must establish, implement and maintain gender neutral remuneration policy and practices that are appropriate and proportionate to the nature, scale and complexity of the risks inherent in the business model and the activities of the Firm.

Governance

The Members are responsible for the Firm’s remuneration policy.

Performance period

The Firm’s performance period is from 1 January to 31 December. The Firm has adopted a Remuneration Policy that complies with the requirements of Chapter 19G of the FCA’s Senior Management Arrangements, Systems and Controls Sourcebook.

Approach to remuneration for employees

The Firm’s remuneration approach is designed to support individual and corporate performance, encourage the sustainable long-term financial health of the business, and promote sound risk management for the success of the Firm and to the benefit of its customers, counterparties and the wider market. Our remuneration approach promotes long-term value creation through transparent alignment with the agreed corporate strategy.

The Members believe that the Firm’s remuneration structure is appropriate for the business and the industry it operates in and is efficient and cost-effective in delivering its long-term strategy.

Our remuneration structure includes provisions that in specific circumstances, allow the Firm to forfeit or withhold all or part of a bonus or long-term incentive award before it has vested and been awarded (‘performance adjustment’ or ‘malus’).

Financial incentives objectives

The objectives of the Firm’s remuneration practices are as follows:

  • the Firm undertakes to reward all employees fairly, regardless of job function, race, religion, colour, national origin, sex, sexual orientation, marital status, pregnancy, disability or age;
  • it is the policy of the Firm to operate competitive remuneration policies to attract, retain and motivate an appropriate workforce for the Firm;
  • the Firm is also committed to ensuring that its remuneration practices encourage high standards of personal and professional conduct, support sound risk management and do not encourage risk taking that exceeds the level of tolerated risk of the Firm, and are aligned with the Firm’s regulatory requirements;
  • rewards for all staff will be aligned to financial and non-financial performance criteria and risk profile, and in all cases will be in line with the business strategy, objectives, values, culture and long-term interests of the Firm;
  • the Firm will not allow any unfair or unjust practices that impact on pay;
  • the Firm undertakes that it will not award remuneration using vehicles or methods the aim of which is to attempt to avoid application of the relevant FCA’s Remuneration Code.
The Firm uses the following financial incentives:

  • bonuses; and
  • salary raises.
Our financial incentives are designed to:

  • raise employee satisfaction;
  • recognise individual performance;
  • attract and retain talent;
  • encourage collaborative teamwork; and
  • motivate staff to achieve Firm-wide objectives.

Governance

The Members are responsible for the Firm’s remuneration policy.

The Members are responsible for reviewing and approving remuneration, and to ensure remuneration policies across the Firm are consistent with the promotion of effective risk management. The Members are responsible for reviewing and approving salary amendments and the Firm’s bonus pool arising from the annual compensation review, with reports made to the Members as required.

The Members of the Firm meet regularly and are:

  • Francesco De Rubertis
  • Richard Lee
  • Giovanni Mariggi
  • Giovanni Pericolini
  • Nicholas Williams

Components of remuneration

The Firm makes a clear distinction between the fixed and variable remuneration.

Fixed remuneration primarily reflects a staff member’s professional experience and organisational responsibility as set out in the staff member’s job description and terms of employment; and is permanent, pre-determined, nondiscretionary, non-revocable and not dependent on performance.

Variable remuneration is based on performance and reflects the long-term performance of the staff member as well as performance in excess of the staff member’s job description and terms of employment.

Variable remuneration includes discretionary pension benefits. The Firm will ensure that the fixed and variable components of an individual’s total remuneration are appropriately balanced. In determining this balance, the Firm considers the following factors:

  • the Firm’s business activities and associated prudential and conduct risks;
  • the role of the individual in the Firm;
  • the impact that different categories of staff have on the risk profile of the Firm;
  • no individual must be dependent on variable remuneration to an extent likely to encourage them to take risks outside the risk appetite of the Firm;
  • it may be appropriate for an individual to receive only fixed remuneration, but not only variable remuneration; and
  • variable remuneration must not affect the Firm’s ability to ensure a sound capital base.
When assessing individual performance to determine the amount of variable remuneration to be paid to an individual, the Firm considers financial as well as non-financial criteria. Non-financial criteria should:

  • form a significant part of the performance assessment process;
  • override financial criteria, where appropriate;
  • include metrics on conduct, which should make up a substantial portion of the non-financial criteria; and
  • include how far the individual adheres to effective risk management and complies with relevant regulatory requirements.

Financial and non-financial performance criteria

The Firm must consider both financial and non-financial criteria when assessing the individual performance of its staff. This aims not only to discourage inappropriate behaviours but also to incentivise and reward behaviour that promotes positive non-financial outcomes for the Firm.

The Firm uses the following financial performance criteria:

  • variable remuneration would only be considered if the Firm is profitable.
The Firm uses the following non-financial performance criteria:

  • measures relating to building and maintaining positive relationships with relevant counterparties, such as positive customer feedback;
  • performance in line with Firm’s strategy or values, for example by displaying leadership, team work or creativity;
  • adherence to the Firm’s risk management and compliance policies;
The criteria outlined above are used for the assessment of the performance of all the individuals employed by the Firm, regardless of the business unit they operate in.

Total amount of remuneration awarded

Under MIFIDPRU 8.6.8R(2), the Firm must disclose the total amount of remuneration awarded to all staff, split into:

  • fixed remuneration; and
  • variable remuneration.

Remuneration type

£000

Fixed remuneration

5,180

Variable remuneration

3,607

Total amount

8,787